CYCLIC STRETCHING-INDUCED EPITHELIAL CELL REORIENTATION IS DRIVEN BY MICROTUBULE-MODULATED TRANSVERSE EXTENSION DURING THE RELAXATION PHASE

Abstract Many types LIQUID EYELINER of adherent cells are known to reorient upon uniaxial cyclic stretching perpendicularly to the direction of stretching to facilitate such important events as wound healing, angiogenesis, and morphogenesis.While this phenomenon has been documented for decades, the underlying mechanism remains poorly understood.Usi

Daratumumab is a humanized anti-CD38 IgG1 monoclonal antibody which could be used for multiple myeloma (MM).MM with plasma-cell leukemia (PCL) transformation is highly aggressive and is resistant to conventional therapy.Novel therapeutics Rear Suspension are needed for PCL, and daratumumab may play role.We report a case of relapsed/refractory multi